What is Bone Marrow ?
Bone marrow is a spongy material found in the hollow centers of some bones. It is important as it contains special cells known as stem cells.
Stem cells create other specialized cells that carry out important functions. Stem cells in bone marrow produce three important types of blood cell:
Bone Marrow Transplantation
Bone marrow transplantation (also known as stem cell transplantation) involves harvesting healthy stem cells to replenish the bone marrow of the patient. The new stem cells take over the production of the blood cells.
In some circumstances, it may be possible to take your own bone marrow from another part of your body (this is known as autologous transplantation). The bone marrow may be cleared of any diseased cells before being returned.
How Bone marrow transplant is performed:
Stages of the Transplant Process
There are five stages in the transplant process:
Why Bone Marrow Transplants are Necessary?
Stem cell transplantations are often required to treat conditions that have damaged the bone marrow which, as a result, can no longer produce normal blood cells. Any disruption to the production of blood cells can be very serious, particularly if:
Some of the conditions that can affect blood and bone marrow are described below.
Leukemia is cancer of the white blood cells. The cancer causes the white blood cells to replicate in an uncontrollable manner and they do not develop any infection-fighting properties.
The cancerous cells can quickly spread through the bloodstream, resulting in a lack of room for red blood cells and platelets.
This leads to symptoms of anemia, increases the risk of serious infection, and means that you will bruise and bleed more easily.
Non-Hodgkin's lymphoma is another type of cancer of the white blood cells. However, rather than spreading through the bloodstream, it spreads through the lymphatic system. The lymphatic system is a series of connected glands (nodes) that are spread throughout your body. It is an important part of your immune system, the body's natural defense against infection.
Inherited (genetic) Blood Disorders
There are a number of genetic blood disorders where alterations (mutations) in your genes mean that blood cells do not develop normally. These include sickle cell anemia and thalassemia, both of which interfere with the production of red blood cells.
Who Can Have a Bone Marrow Transplant?
Stem Cell Transplants are Normally Only Recommended if:
Bone Marrow Transplantation at Yeditepe University Hospital
Over the years, many patients diagnosed with leukemia, lymphoma, myelodysplasia, multiple myeloma and other blood cancers or disorders have come to Yeditepe University Hospital for its great line of service and medical treatment with today’s latest techniques, technology and the region’s most experienced physicians.
Whether you live in Istanbul, across Turkey or around world, specialists at Yeditepe University Healthcare Institutions are available to review your medical records and provide an expert opinion on your diagnosis or treatment plan -without the need for an in- person visit.
Yeditepe University Healthcare Institutions collaborates with digital platforms via tele-medicine, to offer remote second opinions from Yeditepe University Healthcare Institutions in virtually every medical specialty. Having a second opinion can reassure you about a challenging diagnosis, or help you and your doctor plan the most appropriate course of treatment.
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To have a medical second opinion: